diff --git a/gcc/tree-vect-data-refs.cc b/gcc/tree-vect-data-refs.cc
index 4a23d6172aaa12ad7049dc626e5c4afbd5ca3f74..6c892791bd4c39f672add4e4c22a9d7835e292d6 100644
--- a/gcc/tree-vect-data-refs.cc
+++ b/gcc/tree-vect-data-refs.cc
@@ -4016,6 +4016,11 @@ vect_check_gather_scatter (stmt_vec_info stmt_info, loop_vec_info loop_vinfo,
   if (reversep)
     return false;
 
+  /* PR 107346.  Packed structs can have fields at offsets that are not
+     multiples of BITS_PER_UNIT.  Do not use gather/scatters in such cases.  */
+  if (!multiple_p (pbitpos, BITS_PER_UNIT))
+    return false;
+
   poly_int64 pbytepos = exact_div (pbitpos, BITS_PER_UNIT);
 
   if (TREE_CODE (base) == MEM_REF)